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2010-11 Undergraduate Calendar
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2011-2012 Undergraduate Calendar
HOME COURSES Biochemistry (BCH)

Biochemistry (BCH)
BCH 261 Biochemistry
This course deals with the structure, function and chemistry of the molecular building blocks of the cell. This includes a discussion of water and its properties, amino acids, proteins, nucleotides and nucleic acids, carbohydrates and lipids. Also included is an introduction to enzyme function and kinetics. The laboratory provides an introduction to the basic biochemical techniques including chromatography, electrophoresis and spectrophotometry. (Formerly CHY 261).
Lect: 3 hrs./Lab: 3 hrs.
Prerequisite: CHY 142
Course Weight: 1.00
Billing Units: 1
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BCH 361 Advanced Biochemistry I
A course in the principles of enzymology, bioenergetics and carbohydrate metabolism. Enzymology topics include the structure, function and regulation of enzymes and Michaelis-Menten kinetics. The fundamentals of bioenergetics and intermediary metabolism are discussed in the context of the integration and control of catabolism and anabolism. The course concludes with a detailed examination of carbohydrate chemistry with emphasis on the chemical logic and the regulation of these pathways. The laboratory introduces students to more advanced biochemical techniques. Topics include the isolation and characterization of polysaccharides and the kinetic analysis of enzymes. (Formerly CHY 361).
Lect: 3 hrs./Lab: 3 hrs.
Prerequisite: CHY 261 or BCH 261
Course Weight: 1.00
Billing Units: 1
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BCH 362 Advanced Biochemistry II
The major topics introduced in the lectures are membrane structure and transport systems and the metabolism of lipids, proteins and nucleic acids. A review of DNA replication and protein synthesis will also be included. The laboratory focuses on chromatography and electrophoresis as used to separate and analyze proteins. Students are required to write a major report(s), make an oral presentation and present a poster. (Formerly CHY 362).
Lect: 3 hrs./Lab: 3 hrs.
Prerequisite: CHY 361 or BCH 361
Course Weight: 1.00
Billing Units: 1
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BCH 501 Protein Biochem and Proteomics
In depth examination of protein structure and function, tools for determining biochemical function and structure, analysis of protein-protein interactions, regulatory mechanisms, introduction to high throughput identification and quantification of protein expression; application of proteomics to drug design.
Lect: 3 hrs.
Prerequisites: BCH 261 and BCH 361
Course Weight: 1.00
Billing Units: 1
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BCH 580 Cell Signalling
The course provides a survey of signal transduction. Topics include: intracellular, intercellular and signaling between tissues and organs; biophysics and calculation of ligand receptor binding; signaling of prokaryotes required for quorum, chemical and nutrient detection, signaling transduction of mammalian senses and nervous systems. A survey of mammalian signal transduction including the cell surface receptors, the Ig superfamily and cancer signal mechanisms will be presented.
Lect: 3 hrs.
Prerequisite: BLG 311 and (CHY 261 or BCH 261)
Course Weight: 1.00
Billing Units: 1
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