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Research Assistant - Genetically-modified mouse models of cancer

Department: Chemistry and Biology, Faculty of Science
Position supervisor: Dr Michael Olson
Contract length: 2 years
Hours of work per week: 36.25
Position type: Term vacancy
Rate of pay: To be determined
Deadline to apply: Posted until filled

About Ryerson

At the intersection of mind and action, Ryerson is on a transformative path to become Canada’s leading comprehensive innovation university. Integral to this path is the placement of equity, diversity and inclusion as fundamental to our institutional culture. Our current academic plan outlines each as core values and we work to embed them in all that we do.

Ryerson University welcomes those who have demonstrated a commitment to upholding the values of equity, diversity, and inclusion and will assist us to expand our capacity for diversity in the broadest sense. In addition, to correct the conditions of disadvantage in employment in Canada, we encourage applications from members of groups that have been historically disadvantaged and marginalized, including First Nations, Metis and Inuit peoples, Indigenous peoples of North America, racialized persons, persons with disabilities, and those who identify as women and/or 2SLGBTQ+. Please note that all qualified candidates are encouraged to apply; however, applications from Canadians and permanent residents will be given priority.

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About the team

Professor Michael Olson is Canada Research Chair in Molecular Cell Biology and Professor in the Ryerson University Department of Chemistry and Biology. The Olson laboratory is located in newly built biomedical research facilities at the MaRS Discovery District (marsdd.com), external link in downtown Toronto (Queens Park subway station), within one of the highest densities of biomedical research activity in North America, offering an unparalleled environment for networking and collaboration. The Olson lab works on Rho GTPase regulation of the actin cytoskeleton, and the role of associated signaling pathways in cancer. Recent examples of the lab’s work include: (Cancer Lett. 2021 Oct 28;519:226-236, external link; Elife. 2021 Apr 19;10:e61983, external linkSmall GTPases. 2021 Jul;12(4):294-310, external link).

The opportunity

The incumbent will work under the general direction of the Principal Investigator (PI), and will support the PI, students, and post-doctoral fellows (PDFs) in the laboratory. The research responsibilities will include: management of mouse colonies, genotyping, establishment of breeding strategies, drug/compound administration, tissue sampling for IHC, blood sampling, immunohistochemistry, imaging, and sample preparation for analysis such as western blotting, mass spectrometry or RT-PCR. In addition, experiments will also make use of established and primary cell lines, using methods including biochemistry, western blotting, immunofluorescence and RT-PCR.

Qualifications

The ideal candidate holds a Master’s degree or higher in a relevant scientific discipline, such as genetics, immunology or biochemistry. Interested individuals must demonstrate their expertise in the use of genetically modified mice for the study of cancer or immunology. This position will support research projects undertaken by team members, and may span several different areas of investigation. Familiarity with image acquisition software is highly desired, as is familiarity with common image analysis software programs. Experience with safe lab operations, including all safety procedures, restocking lab supplies and reagents, troubleshooting and the ability to provide effective training and orientation to students and other researchers is essential. The incumbent should be highly computer literate, have excellent interpersonal and communication skills, and be able to work in a collaborative and multidisciplinary research group.

How to apply

Please email your application to Michael Olson at michael.olson@ryerson.ca. Applications should be submitted in PDF or word formats. In the subject line please indicate: “Research Assistant - Application”.

Applications should include: CV, cover letter, names of up to 3 references.

We thank all candidates for their interest, however, only candidates who are invited to an interview will be contacted.

Ryerson’s commitment to equity, diversity and inclusion

We encourage all First Nations, Metis and Inuit peoples or Indigenous peoples of North America, to self-identify in their applications and also reach out to Tracey King, Indigenous Human Resources Lead for support during the selection process.

Please watch a message from Ryerson's Vice President, Equity and Community Inclusion for more information on our commitment to equity.

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Following the advice of government and health authorities to slow the spread of COVID-19, all employees have been equipped to work from home until further notice.  New employees will also work from home with the exception of those who have been deemed 'essential' and are required to be on campus.  All recruiting activities including interviews and onboarding are being conducted virtually.  

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